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Drugs in Medicine
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Cambridge IGCSE Biology
    About Lesson

    Explaining the Link Between Physical Activity & Breathing

     

    Why Breathing Rate and Depth Increase During Exercise

    • During exercise, muscle cells work harder and undergo more aerobic respiration to meet the body’s energy demands.

    • To support this, the frequency (rate) and depth of breathing increase.

    • Muscles need:

      • More oxygen delivered to them.

      • More carbon dioxide removed as a waste product of respiration.

     

    What Happens When Demand Exceeds Supply?

    • If oxygen delivery cannot keep up, muscles begin to carry out anaerobic respiration.

    • This leads to the production of lactic acid.

    • Lactic acid lowers the pH of cells and can denature enzymes, disrupting normal cellular activity.

     

    Oxygen Debt & Recovery

    • After exercise, lactic acid must be broken down.

    • This process requires oxygen, known as repaying the oxygen debt.

    • The longer it takes for breathing rate and depth to return to normal, the greater the oxygen debt — indicating more lactic acid was produced during exercise.

     

    Mechanism Behind the Increase in Breathing During Exercise

    1. Increased respiration in muscles produces more carbon dioxide (CO₂).

    2. CO₂ diffuses from muscle cells into the blood plasma.

    3. CO₂ in the blood forms a weak acid, lowering blood pH slightly.

    4. This acidic blood reaches the brain, where chemoreceptors in the medulla oblongata detect:

      • Increased CO₂ levels

      • Decreased pH

    5. In response, the brain sends nerve impulses to:

      • The diaphragm

      • The intercostal muscles

    6. This causes:

      • Increased rate of breathing (inspiration)

      • Greater depth of breathing

     

    Overall Result

    • More oxygen is absorbed into the bloodstream.

    • More carbon dioxide is removed.

    • This supports the high rate of respiration needed by active muscles during physical activity.

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